Thermo Fisher Scientific TrkC Polyclonal Antibody
Rabbit polyclonal antibody recognizing TrkC protein in human, mouse, and rat. Suitable for WB and IHC applications. Lyophilized form, reconstitutable in sterile water. Recommended for neurobiology research. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous (PubMed) | – | View 2 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 780–830 of the cytoplasmic domain of human TrkC conjugated to a blue carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C for short term. For long term storage, store at –20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: TrkC.
Target Information
NTRK3 (TRKC) belongs to the neurotrophic factor receptor family, essential for the development and maintenance of the mammalian nervous system. Known substrates include SHC, PI-3 kinase, and PLCG1. Isoforms have distinct signaling properties. The protein is widely expressed, primarily in nervous tissue. Isoform B is more abundant in the adult brain than in the fetal brain. TRKC undergoes ligand-mediated auto-phosphorylation and contains two immunoglobulin-like C2-type domains and two leucine-rich (LRR) repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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