Thermo Fisher Scientific Filamin B Monoclonal Antibody (GT1372)
Filamin B 단백질 검출용 Mouse 모노클로날 항체 (Clone GT1372). Western blot, IHC, IP에 사용 가능. Human, Mouse, Rat 반응성. Protein G 정제, 1.92 mg/mL 농도. 연구용으로만 사용.
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Thermo Fisher Scientific Filamin B Monoclonal Antibody (GT1372)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1372 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.92 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735182 |
Product Specific Information
- Positive Control: HeLa
- Predicted Reactivity: Chicken (97%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus, and is predominantly expressed in many malignant tissues such as tumors of the brain, colon, and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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