Thermo Fisher Scientific Glutamine Synthetase Monoclonal Antibody (GT1055)
Glutamine Synthetase 단백질을 인식하는 Mouse monoclonal antibody (Clone GT1055). WB, IHC, ICC 등 다양한 응용에 적합하며 Human, Mouse, Rat 반응성. Protein G 정제, 1 mg/mL 농도, PBS buffer. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1055 |
| Immunogen | Full length human Glutamine synthetase recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735204 |
Product Specific Information
- Positive Control: 293T, HeLa, HepG2, U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain, mouse eye, rat brain
- Predicted Reactivity: Xenopus laevis (85%), Dog (97%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Glutamine synthase is part of the glutamine synthetase family. In animals, ammonia incorporation occurs through glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen metabolism, acting as both a nitrogen donor and acceptor. It also regulates neurotransmitter glutamate metabolism.
Glutamine synthetase (GS) activity is tightly regulated, including by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer’s disease and under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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