Thermo Fisher Scientific CLN2 Polyclonal Antibody
CLN2 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응합니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 -20°C 보관, 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TPP1 (Accession O14773), corresponding to amino acid residues S181–L231 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852209 |
Product Specific Information
Antibody detects endogenous levels of total TPP1.
Target Information
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme that becomes activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, associated with failure to degrade specific neuropeptides and an ATP synthase subunit in the lysosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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