Thermo Fisher Scientific CREM Polyclonal Antibody
CREM 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간 및 랫트 반응성. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer에 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CREM (Accession Q03060), corresponding to amino acid residues H102–P152 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852207 |
Product Specific Information
Antibody detects endogenous levels of total CREM.
Target Information
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It plays a key role in cAMP-mediated signal transduction during the spermatogenetic cycle and other complex biological processes. Alternative promoter and translation initiation site usage allow spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encode several isoforms that function as either activators or repressors of transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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