Thermo Fisher Scientific Actin, Smooth Muscle Polyclonal Antibody
Smooth muscle actin을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트에서 반응하며 액상 형태로 제공됩니다. 세포 구조 및 근육 수축 연구에 유용합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 600-410
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 10aa synthetic peptide corresponding to N-term of human Actin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Most cells
- Cellular location: Cytoplasm
Target Information
Smooth Muscle Actin belongs to the actin family of highly conserved proteins involved in cell motility, structure, and integrity.
Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actin: Major constituent of the contractile apparatus
- Beta and gamma actins: Involved in regulation of cell motility
Smooth muscle actin is an alpha actin found in skeletal muscle and smooth muscle vessel walls, gut wall, myometrium, and myoepithelial cells of breast and salivary glands.
Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6.
Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells and also appears in stress fibers of fibroblastic cells during wound healing and fibrocontractive diseases.
Multiple alternatively spliced variants of smooth muscle actin have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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