Thermo Fisher Scientific CD9 Monoclonal Antibody (MM2/57), PE

Thermo Fisher Scientific CD9 Monoclonal Antibody (MM2/57), PE

Applications

• Flow Cytometry (Flow)
  Tested Dilution: Neat-1:2

Product Specifications

Additional Formats

• Unconjugated: MA1-80307
• FITC: MA5-16860
• Custom conjugation available upon request

Product Specific Information

• Predicted to react with mustelid based on sequence homology.
• Reconstitute with 1 mL distilled water.
• After reconstitution, store undiluted at 4°C in the dark.
• For FACS analysis, use 10 µL of working dilution to label 1×10⁶ cells in 100 µL.

Target Information

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and neurons/glial cells in the peripheral nervous system.
It belongs to the tetraspanin family, traversing the membrane four times.
In pre-B cells and platelets, CD9 regulates cell activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
CD9 plays roles in:

• Cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion
• Cell attachment and proliferation
• Association of heterologous MHC II molecules for effective T cell stimulation
• Suppression of cancer cell motility and metastasis (metastasis suppressor in solid tumors)

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

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