Thermo Fisher Scientific Interleukin-2 (IL-2) Monoclonal Antibody (IL2/7359)
인간 IL-2 단백질을 표적으로 하는 마우스 단클론 항체로, IHC(P)에서 1-2 µg/mL로 사용 가능. 면역조직화학 및 세포 위치 연구에 적합하며, 200 µg/mL 농도의 액상 형태로 제공. 단백질 A/G 정제, PBS + BSA 버퍼, 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL2/7359 |
| Immunogen | Recombinant fragment (around aa1–153) of human IL2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human endometrium or tonsil tissue
- Cellular Location: Secreted
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a key role in the proliferation of activated T cells and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared with IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism for precise gene expression.
Disruption of the IL-2-like gene in mice leads to ulcerative colitis-like disease, highlighting its essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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