Thermo Fisher Scientific Interleukin-2 (IL-2) Monoclonal Antibody (IL2/4987)
인간 IL-2 단백질을 인식하는 마우스 단클론 항체로, IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C 보관. 면역조절 관련 연구용으로 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL2/4987 |
| Immunogen | Recombinant fragment (around aa 21–153) of human IL2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a critical role in the proliferation of activated T cells and the differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by interleukins 4 and 7. The monoallelic expression of the IL-2 gene in mature thymocytes represents a unique regulatory mechanism for precise gene control. Disruption of the IL-2 gene in mice results in an ulcerative colitis-like disease, highlighting its essential role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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