Thermo Fisher Scientific Interleukin-2 (IL-2) Recombinant Rabbit Monoclonal Antibody (IL2/7051R)
Recombinant rabbit monoclonal antibody specific for human IL-2. Suitable for IHC applications with assay-dependent or 1–2 µg/mL dilution. High purity (Protein A/G), liquid form, 1 mg/mL concentration. Stored at -20°C, for research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IL2/7051R |
| Immunogen | Recombinant fragment (around aa21–153) of human IL2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). Expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for controlling precise expression of a single gene. Targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, suggesting an essential role of this gene in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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