Thermo Fisher Scientific Interleukin-2 (IL-2) Recombinant Rabbit Monoclonal Antibody (IL2/7051R)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: Assay-dependent

Immunohistochemistry (PFA fixed) (IHC (PFA))

• Tested Dilution: 1–2 µg/mL

Product Specifications

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a key role in the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism for precise gene expression. Disruption of a similar gene in mice results in an ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.