Thermo Fisher Scientific PHD1 Polyclonal Antibody
Thermo Fisher Scientific의 PHD1 Polyclonal Antibody는 Human, Mouse, Rat에 반응하며 Western Blot 및 ELISA에 적합합니다. Rabbit IgG 기반의 액상 항체로, Affinity chromatography로 정제되었으며 1.25 mg/mL 농도입니다. 세포 내 산소 감지 및 성장 조절 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 124–223 of human Prolyl hydroxylase PHD1 (EGLN2) (NP_444274.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901194 |
Product Specific Information
- Positive Samples: Mouse brain, Rat heart
- Immunogen Sequence:
DGGDAPSPSK RPWARQENQE AEREGGMSCS CSSGSGEASA GLMEEALPSA PERLALDYIV PCMRYYGICV KDSFLGAALG GRVLAEVEAL KRGGRLRDGQ
Target Information
Prolyl hydroxylase domain proteins HIF PHD1, HIF PHD2, and HIF PHD3 can hydroxylate HIF-alpha subunits. Hypoxia-inducible factor (HIF) is a transcriptional regulator essential for oxygen homeostasis. PHD1 catalyzes the formation of 4-hydroxyproline in HIF-alpha proteins and acts as a cellular oxygen sensor. It is widely expressed, especially in testis, and found in hormone-responsive tissues such as mammary, ovarian, and prostate epithelium. The PHD1 gene (EGLN2) maps to chromosome 19q13.3.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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(이미지 파일명: PA5-116563_PHD1_Q96KS0-1_Rabbit_PDP.jpeg, PA5-116563_PHD1_Q96KS0-1_Rabbit.svg)
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