Thermo Fisher Scientific Phospho-Crk (Ser41) Polyclonal Antibody
인간 CRK 단백질의 Ser41 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Dot blot에서 1:500 희석으로 검증됨. 단백질 A 및 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.09% sodium azide 포함. 인간 반응성, 마우스 및 랫트 반응 예측됨.
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Applications
- Dot blot (DB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S41 of human CRK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2084889 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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