Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI2A11), TrueMAB
인간 KLK8 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도 유지. PBS 완충액과 트레할로스를 포함하며, 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
The KLK8 gene is part of a kallikrein subfamily cluster on chromosome 19 and may play a role in proteolytic cascades in the skin, as well as serve as a biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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