Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Mouse Monoclonal Antibody (Sb#42)
SARS-CoV-2 스파이크 단백질 RBD를 인식하는 재조합 마우스 모노클론 항체. ELISA 및 다양한 기능적 분석에 적합. HEK293 세포에서 발현된 IgG1 형식으로, Protein A로 정제됨. 비결합형 액상 형태로 연구용으로 사용 가능.
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Applications
ELISA
- Tested Dilution: 1 µg/mL
Functional Assay
- Tested Dilution: Assay-dependent
Inhibition Assays
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1, Fc |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Sb#42 |
| Immunogen | This clone was originally isolated in a form of a synthetic nanobody (sybody) via a target swap selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognizes and binds the SARS-CoV-2 C-terminal receptor binding domain (RBD) located in the extracellular portion of the spike protein.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold symptoms to severe respiratory distress.
The Spike (S) protein is crucial for viral attachment, fusion, and entry, serving as a major target for antibody development, entry inhibitors, and vaccines.
The receptor-binding domain (RBD, S-RBD) in the Spike protein binds strongly to human and bat ACE2 receptors, showing higher affinity than the SARS-CoV RBD.
The S1 subunit contains the RBD that specifically interacts with ACE2 on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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