Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Human Monoclonal Antibody (Sb#16)
SARS-CoV-2 스파이크 단백질 RBD를 인식하는 인간 재조합 단일클론 항체. ELISA 및 기능적 억제 실험에 사용 가능. HEK293 세포에서 발현된 IgA 형식의 항체로, 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Human Monoclonal Antibody (Sb#16)
Applications
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Inhibition Assays (IA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host/Isotype | Human / IgA, Fc |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Sb#16 |
| Immunogen | This clone was originally isolated in a form of a synthetic nanobody (sybody) via a target swap selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
Product Specific Information
This antibody recognizes and binds the SARS-CoV-2 C-terminal receptor binding domain (RBD) located in the extracellular portion of the spike protein.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV (2019 Novel Coronavirus), causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The CoV Spike (S) protein is essential for viral attachment, fusion, and entry, making it a key target for antibody, inhibitor, and vaccine development.
The receptor-binding domain (RBD, S-RBD) binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD shows significantly higher binding affinity to ACE2 than SARS-CoV RBD.
The S1 subunit contains the RBD that specifically binds to ACE2 receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.