Thermo Fisher Scientific IFRD1 Polyclonal Antibody
IFRD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 ELISA에 적합하며 Human, Mouse, Rat 시료에 반응. 고순도 친화 크로마토그래피 정제, 0.53 mg/mL 농도, -20°C에서 보관.
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- PA589158
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–240 of human IFRD1 (NP_0015412) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805393 |
Product Specific Information
Immunogen sequence:
MPKNKKRNTP HRGSSAGGGG SGAAAATAAT AGGQHRNVQP FSDEDASIET MSHCSGYSDP SSFAEDGPEV LDEEGTQEDL EYKLKGLIDL TLDKSAKTRQ AALEGIKNAL ASKMLYEFIL ERRMTLTDSI ERCLKKGKSD EQRAAAALAS VLCIQLGPGI ESEEILKTLG PILKKIICDG SASMQARQTC ATCFGVCCFI ATDDITELYS TLECLENIFT KSYLKEKDTT VICSTPNTVL
Positive Samples: SW480
Target Information
Tis7, also known as IFRD1, is a 442 amino acid membrane-associated, non-nuclear intracellular protein belonging to the IFRD family. It is a regulatory protein expressed in various tissues and plays an important role in regulating gene activity in proliferative and differentiative pathways induced by NGF. Reports suggest that Tis7 may act as an autocrine factor that modulates ligand-induced signaling and augments adaptive responses by stimulating differentiated enterocyte production. It functions as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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