Thermo Fisher Scientific LOX-1 Recombinant Rabbit Monoclonal Antibody (014)

Applications

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Cynomolgus OLR1/LOX1.

Target Information

LOX-1 (lectin-like oxidized LDL receptor-1) is a 40–50 kDa type II membrane glycoprotein belonging to the class E scavenger receptor family. It is expressed by endothelial cells, macrophages, activated platelets, and smooth muscle cells.

LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite-modified high-density lipoprotein (HDL), aged/apoptotic cells, activated platelets, and bacteria, reflecting its versatile physiological functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.