Thermo Fisher Scientific Bcl-X (Apoptosis Marker) Monoclonal Antibody (BX006)
Bcl-X 단백질을 표적하는 Thermo Fisher Scientific의 BX006 단클론 항체로, apoptosis 연구용 마커로 적합. Western blot과 IHC에 사용 가능하며, 인간, 마우스, 돼지, 랫트 반응성. 고순도 Protein A/G 정제, PBS 기반 액상 형태로 제공.
- 카탈로그번호
- 598-MSM1-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Bcl-X (Apoptosis Marker) Monoclonal Antibody (BX006)
Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BX006 |
| Immunogen | A synthetic peptide, aa 3–14 (Cys-QSNRELVVDFLS) of human Bcl-X protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. These proteins are located at the outer mitochondrial membrane and regulate the opening of the mitochondrial membrane channel (VDAC). VDAC controls mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release — all key factors in apoptosis induction.
Alternative splicing results in multiple transcript variants encoding two isoforms: the longer isoform acts as an apoptotic inhibitor, while the shorter isoform functions as an apoptotic activator.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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