Thermo Fisher Scientific CHRM2 Polyclonal Antibody
CHRM2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 다양한 종에 반응하며, IHC(P) 등 연구용으로 사용됩니다. 항원 친화 크로마토그래피로 정제되었고, 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific CHRM2 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Guinea pig, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550808 |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor may also mediate smooth muscle contractility.
In Alzheimer’s disease, selective loss of M2 subtype receptors occurs in cortical and hippocampal regions of the human brain. Increased M2 receptor heterozygosity has been associated with depression in women.
The M2 receptor is expressed in various brain regions including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, as well as in lung and prostate tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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