Thermo Fisher Scientific CHRM3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CHRM3 (M3 muscarinic receptor). Validated for IHC (paraffin) with high specificity. Supplied as liquid, 1 mg/mL, unconjugated. Recommended storage at 2–8°C short-term or −20°C long-term. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested dilution: 72 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from C-terminus of human CHRM3 / M3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at −20°C. |
| Shipping conditions | Wet ice |
| RRID | AB_2550811 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%).
Target Information
The muscarinic cholinergic receptors belong to the G protein-coupled receptor family. Their functional diversity is defined by acetylcholine binding and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degradation, and potassium channel mediation. Muscarinic receptors influence many acetylcholine-mediated effects in both the central and peripheral nervous systems. The muscarinic cholinergic receptor 3 (CHRM3) controls smooth muscle contraction and its stimulation causes glandular secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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