Thermo Fisher Scientific CHRM2 Polyclonal Antibody
CHRM2 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody입니다. IHC(P) 적용 가능하며, 인간 및 다양한 종에서 반응합니다. 항원 친화 크로마토그래피로 정제되었고 PBS 버퍼에 0.1% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA533430
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CHRM2 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Non-human primate, Sheep, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CHRM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550810 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Sheep, Bovine, Elephant, Panda, Rabbit, Platypus (100%).
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor that may function as a presynaptic autoreceptor inhibiting acetylcholine release. The M2 receptor mediates smooth muscle contractility and is implicated in Alzheimer’s disease due to selective loss in cortical and hippocampal regions. Increased M2 receptor heterozygosity has been associated with depression in women. The M2 receptor is expressed in multiple brain regions including cerebellum, cerebral cortex, hippocampus, medulla, striatum, thalamus, and also in lung and prostate.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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