Thermo Fisher Scientific AMACR Polyclonal Antibody
AMACR 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–138 of human AMACR (NP_0551394) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804658 |
Product Specific Information
Immunogen sequence:
MALQGISVVE LSGLAPGPFC AMVLADFGAR VVRVDRPGSR YDVSRLGRGK RSLVLDLKQP RGAAVLRRLC KRSDVLLEPF RRGVMEKLQL GPEILQRENP RLIYARLSGF GQSGSFCRLA GHDINYLALS GVLSKIGR
Positive Samples: Mouse liver
Cellular Location: Mitochondrion, Peroxisome
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme involved in the β-oxidation of branched-chain fatty acids. High expression of P504S protein is observed in prostatic adenocarcinoma, but not in benign prostate tissue, by immunohistochemical staining in paraffin-embedded samples. Expression is also detected in premalignant prostate lesions such as high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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