Thermo Fisher Scientific NOD2 Polyclonal Antibody
Human NOD2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer와 sodium azide를 포함. 세포 내 NOD2 단백질 검출 및 염증 관련 연구에 적합.
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Applications
- Western Blot (WB): 2–4 µg/mL
- Immunocytochemistry (ICC/IF): 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to 14 amino acids at the carboxy terminus of human NOD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153956 |
Product Specific Information
- Suggested positive control: HeLa cell lysate
- PA5-19992 can be used with blocking peptide PEP-0307.
Target Information
NOD2 is a member of the apoptosis regulating protein family that includes caspase recruitment-domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs).
NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues).
NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-19992_NOD2_Q9HC29-1_Rabbit.svg)
(이미지: PA5-19992_NOD2_Q9HC29-1_Rabbit_PDP.jpeg)
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