Thermo Fisher Scientific CARD9 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 2.5 µg/mL
• Publications: View 1 publication

Immunocytochemistry (ICC/IF)

• Tested Dilution: 10 µg/mL
• Publications: -

Product Specifications

Product Specific Information

In Western blot applications, this antibody detects a band at approximately 59 kDa.
A suggested positive control is PC-3 cell lysate.
PA5-19993 can be used with blocking peptide PEP-0115.

Target Information

The protein encoded by this gene belongs to the CARD protein family, characterized by the caspase-associated recruitment domain (CARD).
CARD domains mediate protein-protein interactions involved in activation or suppression of caspase family members, playing a regulatory role in apoptosis.
CARD9 associates selectively with the CARD domain of BCL10, a positive regulator of apoptosis and NF-κB activation, functioning as a scaffold for assembly of the BCL10 signaling complex that activates NF-κB.
Several alternatively spliced transcript variants exist, though their full-length nature is not clearly defined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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