Thermo Fisher Scientific NOD2 Polyclonal Antibody
NOD2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunocytochemistry에 사용 가능. Human 시료 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태로 제공되며, 냉장 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at −20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153381 |
Product Specific Information
- A suggested positive control is Jurkat cell lysate.
- PA5-19991 can be used with blocking peptide PEP-0306.
Target Information
NOD2 is a member of the apoptosis-regulating protein family that includes caspase recruitment domains, as well as Apaf-1 and NOD1. It contains two N-terminal CARDs, a nucleotide-binding domain (NBD), and multiple C-terminal leucine-rich repeats (LRRs).
NOD2 is expressed in monocytes (whereas NOD1 is expressed in multiple tissues). NOD2 plays a role in regulating NF-kappaB, acts as an intracellular receptor for bacterial lipopolysaccharides, and contributes to inflammatory bowel disease (IBD) and Crohn’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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