Thermo Fisher Scientific CD81 Monoclonal Antibody (Eat2)
Mouse 및 Rat 시료에서 CD81 단백질을 검출하는 Armenian hamster 유래 monoclonal antibody. Flow cytometry 및 IHC에 적합하며, 비결합(Unconjugated) 형태로 제공. Protein G 정제, PBS buffer에 0.02% sodium azide 포함. 장기보관은 -20°C 권장.
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Applications
Immunohistochemistry (IHC)
- Tested dilution: Not specified
- View 1 publication
Flow Cytometry (Flow)
- Tested dilution: 1 µg / 1 million cells
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Eat2 |
| Immunogen | Tissue / cell preparation (Mouse 38C13 cell line) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2076271 |
Additional Formats
Product Specific Information
- MA1-70091 detects CD81 in mouse and rat samples.
- Successfully used in flow cytometry procedures.
- Immunogen derived from mouse 38C13 cell line tissue/cell preparation.
Target Information
CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family expressed on most nucleated cells, especially germinal center B cells.
It forms complexes with tetraspanin proteins, integrins, MHC molecules, and coreceptors, influencing adhesion, activation, proliferation, and differentiation of B and T cells.
In muscles, CD81 promotes cell fusion and myotube maintenance. It also acts as a receptor for hepatitis C virus.
Antibodies to CD81 can have anti-proliferative effects on lymphoid cell lines, particularly large cell lymphomas.
CD81 is localized in the tumor-suppressor gene region and is considered a candidate gene for malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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