Thermo Fisher Scientific Phospho-Shp2 (Tyr580) Recombinant Rabbit Monoclonal Antibody (Shp2Y580-4A2), APC
APC 형광 표지된 재조합 토끼 단일클론 항체로, 인산화 Shp2 (Tyr580)을 특이적으로 인식합니다. 인간 및 생쥐 시료에 반응하며 Flow Cytometry에 적합합니다. 고순도 Protein A/G 정제 및 안정적인 PBS/BSA 저장 버퍼를 사용합니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Shp2Y580-4A2 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr580 of human phospho Shp2 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897198 |
Additional Formats
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates diverse cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation. It contains two tandem Src homology-2 domains that mediate phospho-tyrosine interactions with substrates. This PTP is widely expressed and plays a regulatory role in cell signaling related to mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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