Thermo Fisher Scientific Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), APC
APC 형광 표지된 재조합 Rabbit Monoclonal 항체로, 인간, 생쥐, 랫트 ASK1의 Ser83 인산화 형태를 특이적으로 인식합니다. Flow Cytometry에 최적화되어 있으며, 고순도 Protein A/G 정제 및 안정적인 PBS-BSA buffer로 제공됩니다.
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Thermo Fisher Scientific Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Ask1S83-G4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897197 |
Additional Formats
- Unconjugated (MA5-36973)
- FITC (MA5-36975)
- PE (MA5-36974)
- Request custom conjugation available
Target Information
MAP3K5 (ASK1) is a serine/threonine kinase abundantly expressed in human heart and pancreas. It is activated in response to cytokines, growth factors, and environmental stresses. ASK1 activates MAPKKs MKK4 and MKK6, which in turn activate JNK and p38 MAP kinases. ASK1/MAPKKK5 is activated by TNFR and Fas through interactions with TRAF family members and Daxx. Overexpression induces apoptosis, while catalytically inactive ASK1 inhibits TNF-α-induced apoptosis. ASK1 is expressed in various human and mouse tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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