Thermo Fisher Scientific Phospho-NDRG1 (Thr346) Recombinant Rabbit Monoclonal Antibody (NDRG1T346-F5), FITC
FITC 형광 표지된 인산화 NDRG1 (Thr346) 특이 재조합 토끼 단일클론 항체로, 인간 및 생쥐 시료에 반응. Flow cytometry에 적합하며, 고순도 Protein A/G 정제. 세포 성장 및 분화 관련 연구용으로 활용 가능.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NDRG1T346-F5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr346 of human phospho NDRG1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897200 |
Additional Formats
- Unconjugated
- APC
- PE
- Custom conjugation available upon request
Target Information
NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth, and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, segmental demyelination and remyelination, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 acts as a growth inhibitory marker and is expressed in placental membranes, prostate, kidney, small intestine, ovary, colon, and luminal border cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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