Thermo Fisher Scientific FAM111B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FAM111B. Recombinant protein control fragment (Product #RP-97540). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM111B,uniProtId:Q6SJ93-1,ncbiNodeId:9606,antigenRange:3-89,antigenLength:734,antigenImageFileName:PA5-58474_FAM111B_Q6SJ93-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58474_FAM111B_Q6SJ93-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641223

Product Specific Information

Immunogen sequence: SMKTEENKSF SAMEDDQRTR PEVSKDTVMK QTHADTPVDH CLSGIRKCSS TFKLKSEVNK HETALEMQNP NLNNKECCFT FTLNGNS

Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 24%.

Target Information

FAM111B is a 734 amino acid protein that is encoded by a gene that maps to human chromosome 11, which makes up around 4% of human genomic DNA and isconsidered a gene and disease association dense chromosome.The chromosome 11 encoded Atmgene isimportant for regulation ofcellcycle arrest and apoptosisfollowing double strand DNA breaks. Atmmutation leads to the disorderknown as ataxia-telangiectasia. The blood disorders Sickle cell anemia and beta thalassemia are caused by HBB genemutations. Wilms` tumors, WAGR syndrome and Denys-Drash syndrome are associatedwithmutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associatedwith defectsin chromosome 11.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.