Thermo Fisher Scientific FGFR1 Recombinant Rabbit Monoclonal Antibody (10A9)
FGFR1 단백질을 인식하는 재조합 토끼 단클론 항체로, IHC, ICC/IF, Flow Cytometry, ELISA 등 다양한 응용에 적합. HEK293 세포에서 발현되었으며, 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:200 |
| Flow Cytometry (Flow) | 1:20–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10A9 |
| Immunogen | Recombinant Human FGFR1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092451 |
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family (FGFR1–4), a group of membrane-spanning tyrosine kinases that serve as high-affinity receptors for 17 growth factors (FGF1–17). The FGF receptor family plays an important role in mesoderm induction and patterning, cell growth and migration, organ formation, and bone growth. FGFR1 is alternatively spliced, generating multiple splice variants that are differentially expressed during embryonic development and in adults. Mutations or defects in FGFR1 are associated with several diseases, including Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly, Jackson-Weiss syndrome, and Antley-Bixler syndrome. Chromosomal aberrations involving FGFR1 are linked to stem cell myeloproliferative disorders and stem cell leukemia lymphoma syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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