Thermo Fisher Scientific RHD Recombinant Mouse Monoclonal Antibody (28D12)
RHD 단백질을 인식하는 Recombinant Mouse Monoclonal Antibody(28D12)로, Flow Cytometry 및 ELISA에 적합합니다. HEK293 세포에서 발현되었으며, 높은 순도의 액상 형태로 제공됩니다. 인체 RHD 항원 연구용으로 사용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:20–1:500
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 28D12 |
| Immunogen | Recombinant Human RHD protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.87 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092483 |
Target Information
The Rhesus (Rh) blood group system represents one of the most complex and important systems in humans. Two highly homologous genes RHD and RHCE (collectively referred to as RH30 or RHCED) encode the antigens of the Rh blood group system. These tightly linked genes map to human chromosomal position 1p34.1–1p36.
The RHD gene, commonly deleted from a large segment of the population, encodes the most potent blood group immunogen, the D antigen. Rh incompatibility between maternal and fetal blood types can result in hemolytic disease of the newborn (HDN), which may cause fetal death. The RHCE gene exists in four allelic forms, each determining the expression of two antigens in Ce, ce, cE, or CE combinations. The RHCED antigens are integral membrane proteins containing 12 transmembrane helices that maintain erythrocyte membrane integrity. Presentation of Rh antigenic activity requires complex formation between RHCED antigens and RHAG (RH50).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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