Thermo Fisher Scientific TK1 Recombinant Rabbit Monoclonal Antibody (15A5)
인간 TK1 단백질을 인식하는 재조합 토끼 단클론 항체입니다. IHC(P)와 ELISA에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. HEK293 세포에서 발현되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 15A5 |
| Immunogen | Recombinant Human TK1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.65 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092682 |
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5′-phosphate + ADP.
This enzyme is essential for incorporating deoxythymidine into DNA and plays a role in the mechanism of many antiviral drugs such as azidothymidine (AZT). TK1 is also used in selecting hybridoma cell lines for monoclonal antibody production. Clinically, TK1 serves as a marker associated with cell proliferation, as it is expressed in anticipation of cell division.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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