Thermo Fisher Scientific WNT10A Polyclonal Antibody
WNT10A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 IHC(P)에서 검증됨. 인간 및 랫트 반응성. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WNT10A (Accession Q9GZT5), corresponding to amino acid residues C61–E111 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852240 |
Product Specific Information
Antibody detects endogenous levels of total Wnt10a.
Target Information
The WNT gene family consists of structurally related genes encoding secreted signaling proteins involved in oncogenesis and developmental processes such as cell fate regulation and embryonic patterning.
WNT10A is strongly expressed in promyelocytic leukemia and Burkitt’s lymphoma cell lines. It is coexpressed with WNT6 in colorectal cancer cell lines. Overexpression may contribute to carcinogenesis via activation of the WNT–beta-catenin–TCF signaling pathway.
Both WNT10A and WNT6 genes are located in the chromosome 2q35 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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