Thermo Fisher Scientific SMC3 Polyclonal Antibody
Thermo Fisher Scientific의 SMC3 Polyclonal Antibody는 인간 및 마우스 시료에서 SMC3 단백질을 검출하는 토끼 유래 다클론 항체입니다. Western blot과 IHC(P)에서 사용 가능하며, 고순도의 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- PA5102847
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMC3 (Accession Q9UQE7), corresponding to amino acid residues F1040–V1090 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852236 |
Product Specific Information
Antibody detects endogenous levels of total Bamacan.
Target Information
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein.
The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.
Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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