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Thermo Fisher Scientific PYDC1 Polyclonal Antibody
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Thermo Fisher Scientific PYDC1 Polyclonal Antibody

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Thermo Fisher Scientific의 PYDC1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB 및 IHC(P) 실험에 적합합니다. 합성 펩타이드 면역원으로 제작된 Rabbit IgG 항체로, NF-κB 및 pro-caspase-1 활성화 연구에 유용합니다. 연구용 한정 제품입니다.

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Thermo Fisher Scientific PA5102846 PYDC1 Polyclonal Antibody 100 ul pk판매 단위 pk
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627,600원VAT 포함 690,360원

Thermo Fisher Scientific · Thermo Fisher Scientific PYDC1 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:50–1:200

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthesized peptide derived from human PYDC1 (Accession Q8WXC3), corresponding to amino acid residues M1–P31
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS, pH 7.4, with 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C
Shipping Conditions Wet ice
RRID AB_2852235

Product Specific Information

Antibody detects endogenous levels of total ASC2.

Target Information

ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-κB and pro-caspase-1 activation.
It suppresses the kinase activity of the NF-κB inhibitor kinase (IKK) complex, downregulates NF-κB–inducible genes, and inhibits NF-κB activation by cytokines and LPS.


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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