Thermo Fisher Scientific TNFRSF14 Polyclonal Antibody
TNFRSF14 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 랫트 시료에 반응하며 WB와 IHC(P) 실험에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNFRSF14 (Accession Q92956), corresponding to amino acid residues G220–E270 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900690 |
Product Specific Information
Antibody detects endogenous levels of total TNFRSF14.
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily. It acts as a cellular mediator of herpes simplex virus (HSV) entry through binding of HSV envelope glycoprotein D (gD). The cytoplasmic region interacts with TRAF family members, mediating signal transduction pathways that activate immune responses. In T cells, TNFRSF14 activation promotes proliferation and cytokine production, contributing to inflammation and enhanced CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants have been described, though some full-length forms remain undetermined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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