Thermo Fisher Scientific TOM1L2 Polyclonal Antibody
TOM1L2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드 면역원 사용, 액상 형태로 -20°C 보관. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TOM1L2 (Accession Q6ZVM7), corresponding to amino acid residues Q389–E439 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900693 |
Product Specific Information
Antibody detects endogenous levels of total TOM1L2.
Target Information
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain, both typically involved in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. It interacts with Tollip, clathrin, and ubiquitin, and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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