Thermo Fisher Scientific ZC3H8 Monoclonal Antibody (OTI5B12), TrueMAB
ZC3H8 단백질을 표적하는 마우스 단클론 항체로, Western blot에 적합합니다. 정제된 Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 인산완충용액(PBS) 기반 보관, 연구용 전용 제품입니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B12 |
| Immunogen | Full length human recombinant protein of human ZC3H8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter.
It binds specifically to the 5'-AGGTCTC-3' sequence within the intronic regulatory region (IRR) of the GATA3 gene.
Overexpression of ZC3H8 induces thymocyte apoptosis, suggesting its role in thymocyte homeostasis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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