Thermo Fisher Scientific TARBP2 Monoclonal Antibody (OTI2C12), TrueMAB
TARBP2 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(Paraffin) 검증 완료. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 연구용으로 miRNA 처리 및 RISC 복합체 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C12 |
| Immunogen | Full length human recombinant protein of human TARBP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TRBP (TAR RNA-binding protein) is a member of the dsRNA-binding protein family. It contains two highly conserved dsRNA-binding domains and a C-terminal basic region.
This protein binds to HIV-TAR RNA, stimulating expression of HIV-1 long terminal repeats, and inhibits host antiviral mechanisms by binding to IFN-regulated PKR.
TRBP associates with Ago2 to form part of the Dicer-containing complex, playing a key role in microRNA processing and RISC assembly.
It is also implicated in promoting cellular growth and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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