Thermo Fisher Scientific Chromogranin A Monoclonal Antibody (LK2H10)
Chromogranin A 단백질을 인식하는 Mouse Monoclonal Antibody (LK2H10). Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Human, Mouse, Rat, Chicken 반응성. Protein A 정제, 액상 형태로 제공되며 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific Chromogranin A Monoclonal Antibody (LK2H10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LK2H10 |
| Immunogen | A synthetic peptide corresponding to the internal segment of human Chromogranin A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human pancreas
- Cellular Location: Secreted, Neuroendocrine and endocrine secretory granules
Target Information
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins.
It is found in secretory vesicles of neurons and endocrine cells.
CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin.
These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system.
CHGA is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors.
Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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