Thermo Fisher Scientific CLIP1 Polyclonal Antibody, Biotin
CLIP1 단백질을 인식하는 Biotin 결합 염소 유래 폴리클로날 항체. Western blot 및 Peptide ELISA에 적합하며 인간 CLIP1 단백질의 두 가지 isoform을 모두 인식. 안정적인 액상 형태로 제공되며 -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PHSTHHGSRGEERP |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2933138 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_002947.1; NP_937883.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
CLIP170 was initially identified as a new type of intermediate filament-associated protein highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin’s disease.
It is located at microtubule plus ends and required for the binding of endocytic carrier vesicles.
CLIP170 interacts with LIS1 to regulate dynein/dynactin binding to microtubules and may influence lamellipodia formation and cell invasion in breast cancer cells by modulating kinesin and IQGAP1 release.
At least two isoforms of CLIP170 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-142491_CLIP1_P30622-3_Goat.svg 및 PA5-142491_CLIP1_P30622-3_Goat_PDP.jpeg)
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