Thermo Fisher Scientific SFPQ Polyclonal Antibody
SFPQ 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. 인간 시료에 반응하며 IHC(P) 등 다양한 응용에 적합합니다. 고순도 정제 및 안정적 저장 조건으로 신뢰성 높은 연구용 시약입니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 3–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RGREEYEGPNKKPR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933141 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
SFPQ, also known as PSF, encodes a nuclear factor involved in splicing and regulation of gene expression. It forms a heteromer with NONO and participates in DNA pairing and break repair. Recent studies identified SFPQ as a downstream target of tau, showing nuclear depletion and cytoplasmic accumulation in Alzheimer’s disease (AD) brains. Reduced SFPQ levels correlate with tau pathology, suggesting its role in neurodegenerative diseases including AD. SFPQ protein may appear as 47 kDa, 52 kDa, or 100 kDa molecules in various cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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