Thermo Fisher Scientific PTGDR Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total PTGDR.

Target Information

The protein encoded by this gene is a G-protein-coupled receptor functioning as a prostanoid DP receptor. Its activity is mainly mediated by G-S proteins that stimulate adenylate cyclase, resulting in elevated intracellular cAMP and Ca²⁺ levels. Knockout studies in mice suggest that its ligand, prostaglandin D₂ (PGD₂), acts as a mast cell-derived mediator triggering asthmatic responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.