Thermo Fisher Scientific BVES Polyclonal Antibody
BVES 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Paraffin)에서 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. PBS/glycerol 완충액에 보관하며 -20°C에서 안정적.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BVES (Accession Q8NE79), corresponding to amino acid residues S174–N224 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851713 |
Product Specific Information
Antibody detects endogenous levels of total BVES.
Target Information
Blood vessel epicardial substance (BVES), also known as Popeye protein 1, is a transmembrane protein involved in cell-cell interactions and adhesion, particularly at tight junctions.
BVES consists of an extracellular amino-terminus, three transmembrane domains, and a cytoplasmic carboxyl-terminus.
It is expressed in the developing coronary vascular system, including the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme, and vascular smooth muscle cells.
BVES functions in directing the development of heart, epithelial, and muscle cells during embryogenesis and accumulates at cell-cell contact points, such as filopodia and cell borders, promoting adhesion prior to E-cadherin arrival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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