Thermo Fisher Scientific Phospho-PKMYT1 (Ser83) Polyclonal Antibody
PKMYT1 단백질의 인산화 형태(Ser83)를 인식하는 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 제품으로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer83 of human Myt1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977678 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which bind to promoter regions of proteolipid proteins in the central nervous system and play a role in neural development.
Myt1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian CNS.
Recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bind the same cis regulatory element in the PLP1 promoter in vitro, and DNA binding requires Zn²⁺ but not other divalent cations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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