Thermo Fisher Scientific Phospho-MEK1 (Thr286) Polyclonal Antibody
Phospho-MEK1 (Thr286) 특이적 Rabbit Polyclonal Antibody로, Human, Rat, Non-human primate 반응성. Western blot, ICC/IF, Flow cytometry, IP에 사용 가능. 항원 친화 크로마토그래피 정제 및 보존제 무첨가, 연구용으로만 사용.
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-MEK1 (Thr286) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pThr286 of human MEK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 46 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10987325 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with phosphorylated MEK2.
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation.
MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx.
MEK1 is activated by phosphorylation of serine 218 and 222 residues by Raf1.
It is involved in signaling during stress-activated response, apoptosis, and proliferative induction by cytokines.
Mutations in the gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-17664_MEK1_Q02750-1_Rabbit.svg)
(이미지: PA5-17664_MEK1_Q02750-1_Rabbit_PDP.jpeg)
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