Thermo Fisher Scientific MCM5 Monoclonal Antibody (CRCT5.1)
인간 MCM5 단백질을 인식하는 CRCT5.1 클론의 마우스 단클론 항체. Western blot, IHC, ICC 등 다양한 응용 가능. Protein A로 정제된 액상 형태로 제공되며, 장기 보관 시 -20°C 권장. DNA 복제 개시 및 세포 주기 조절 연구에 적합.
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Thermo Fisher Scientific MCM5 Monoclonal Antibody (CRCT5.1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CRCT5.1 |
| Immunogen | Bacterially expressed human MCM5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_934584 |
Product Specific Information
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for staining of paraffin sections.
A suggested positive control for immunohistochemical applications is tonsil or cervical carcinoma.
Mouse anti-Human MCM5 antibody, clone CRCT5.1, recognizes human MCM5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46.
Target Information
The protein encoded by this gene is structurally similar to the CDC46 protein from S. cerevisiae, which is involved in the initiation of DNA replication.
It belongs to the MCM family of chromatin-binding proteins and interacts with other members of this family.
The encoded protein is upregulated during the transition from G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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