Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3764)
인간 ACE/CD143 단백질을 인식하는 Mouse IgG1 단일클론 항체로, IHC, ELISA, Peptide Array 등에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4)에 보존제 없이 제공. -20°C 보관, 연구용 전용.
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- 1636-MSM4-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACE/3764 |
| Immunogen | Full-length recombinant human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme that catalyzes the conversion of angiotensin I into angiotensin II, a physiologically active peptide. Angiotensin II acts as a potent vasopressor and aldosterone-stimulating factor, regulating blood pressure and fluid-electrolyte balance. The enzyme is a key component of the renin-angiotensin system. Variations in the presence of a 287 bp Alu repeat element within this gene have been linked to circulating enzyme levels and cardiovascular pathophysiologies. The gene produces two major isoforms—the somatic and testicular forms—both enzymatically active. Additional alternatively spliced variants have been identified but are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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